PULCEIC

Preservation and Understanding of Life and Consciousness Exploration Industries Corporation

As humanity transitions to become a multiplanetary species, interplanetary travel will be inevitable. However, outside the Earth’s protective environment, the human body is pushed to a point that it did not evolve to tolerate. For example, ionizing radiation can cause DNA damage and elevate long-term cancer risk, while microgravity reduces bone density and accelerates muscle atrophy and can contribute to vision-threatening neuro-ocular changes that jeopardize mission performance and crew health. Therefore, humans are not yet adapted to withstand these interplanetary missions without accumulating serious health risks.

At PULCEIC, our mission is to enable and enhance the biological adaptations necessary for long-duration space missions. We believe the solution lies in advancing novel gene therapies and multiplex gene editing technologies. Our long-term vision is to advance these technologies safely and ethically to mitigate the biological limits of deep space exploration. Therefore, we are building a pipeline to identify, validate, and advance space-relevant genetic countermeasures. Alongside gene therapy and genome editing, we study extremophile organisms that thrive in environments with high radiation, extreme temperatures, desiccation, and high pressure, including glaciers, deep-sea hydrothermal vents, deserts, volcanic systems and polar regions. By identifying the genetic mechanisms that enable their resilience, we aim to incorporate nature’s most effective strategies into the research pipeline.

To complement our biological approach to radiation protection, PULCEIC is also developing AEGIS, an active radiation shielding project designed to protect crew and critical systems from cosmic radiation. While our gene therapies enhance cellular resilience and DNA repair mechanisms against residual radiation-induced damage, AEGIS aims to reduce the radiation dose astronauts receive in the first place. Together, AEGIS serves as the primary interceptor to lower cumulative exposure upstream, while our genetic countermeasures mitigate the effects of any particles or rays that penetrate the shield.

We are driven by a singular ambition, which is to help humanity become a multi-planetary species by expanding biological capabilities and developing protective technologies through science and discoveries that will allow life to survive, adapt and thrive in space. We believe the path to interplanetary civilization will be shaped not only by advances in rockets and propulsion, but also by our ability to adapt biology and engineer the defenses needed for life beyond Earth. We are building toward that future with intention, ambition, and the belief that the preservation and adaptation of life across space is one of the most important quests of our time.

Let there be PULCEIC.

Reach out to us at hello@pulceic.com

Marcus Cheng | Talha Zubair | Nathan Stewart | Federico Granados Unger